通俗翻译Interactions with macrophages in liver metastases were found to drive T cell killing in a Fas-depen- dent manner. Interestingly, this effect was overcome in preclini- cal models via liver-directed radiotherapy—which eliminated these immunosuppressive macrophages and consequently reduced T cell siphoning. Given that patients with liver metas- tasis were also found to have reduced T cell numbers, diversity, and function, these results may have important implications for strategies to improve immunotherapy efficacy for this patient cohort

这项研究发现，在肝转移瘤中，巨噬细胞与T细胞的相互作用以Fas依赖的方式驱动T细胞的杀伤作用。有趣的是，在临床前模型中，通过肝向放疗，这种影响被克服了——这消除了这些免疫抑制性巨噬细胞，从而减少了T细胞的“流失”。鉴于肝转移瘤患者也发现T细胞数量、多样性和功能的减少，这些结果可能对改善这类患者的免疫治疗效果的策略具有重要意义。

相关问题

focal self-attention for local-global interactions in vision transformers

Focal Self-Attention for Local-Global Interactions in Vision Transformers是指在视觉转换器中使用聚焦自我注意力机制来实现局部和全局交互的技术。这种技术可以帮助模型更好地理解图像中的局部和全局信息，从而提高视觉任务的性能。

请从学术角度对这段话进行扩写并润色：single-cell and spatial transcriptomics have been applied to the field of oncology, which can greatly decipher the cellular subpopulations and spatial distribution in the tumor microenvironment and reveal the mechanisms of cell-cell interactions.

单细胞和空间转录组技术已经应用于肿瘤学领域，它们可以深入解析肿瘤微环境中的细胞亚群组成和空间分布，揭示细胞间相互作用的机理。此外，这些技术还可以揭示肿瘤治疗中细胞群落的动态变化，为改善肿瘤患者的治疗效果提供有效的参考。