The generated electrons are transferred to the gate and flow through the gate external circuit while the generated protons (cations) are forced to diffuse from the gate, through the electrolyte and eventually into the channel by the electric field caused by the gate voltage, inducing a further de-doping of the channel (Figure S2c). [15a,16a,16b] Therefore, the additions of glucose result in decreases in the channel current (Figure 2a and S3a). According to the Bernards model and the Nernst equation, the channel current is modulated by Reaction (2) and thus sensitive to the concentration of glucose in PBS solution (See the working mechanism of OECT-based biosensors in the SI).

产生的电子被转移到栅极并通过栅外电路流动，而产生的质子（阳离子）被迫通过栅电压引起的电场从栅极扩散，通过电解质最终进入通道，诱导通道的进一步去掺杂（图S2c）。因此，葡萄糖的加入导致通道电流下降（图2a和S3a）。根据Bernards模型和Nernst方程，通道电流受到反应（2）的调制，因此对PBS溶液中葡萄糖浓度敏感（请参见SI中基于OECT的生物传感器的工作机制）。