History of BNCT
时间: 2024-06-12 20:06:26 浏览: 61
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Boron neutron capture therapy (BNCT) is a therapeutic technique that uses a combination of boron-containing compounds and neutron radiation to target cancer cells. The history of BNCT can be traced back to the 1930s, when researchers first discovered that boron could absorb neutrons and become radioactive.
In the 1950s, researchers began to explore the potential of BNCT for cancer treatment. The first experiments involved injecting boron-containing compounds into animals with tumors and exposing them to neutron radiation. The results were promising, showing that the boron compounds could selectively accumulate in the tumor cells and that neutron irradiation could effectively kill the cancer cells.
In the 1960s and 1970s, BNCT research continued to advance, with the development of more effective boron compounds and neutron sources. The first clinical trials of BNCT were conducted in the 1980s, primarily in Japan and the United States. These early trials showed that BNCT could be effective in treating certain types of cancer, including brain tumors and melanoma.
Since then, BNCT has continued to be studied and refined. Today, BNCT is considered a promising treatment option for a variety of cancers, particularly those that are difficult to treat with traditional therapies. Ongoing research is focused on improving the effectiveness and safety of BNCT, as well as expanding its use to more types of cancer.
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