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第
46
卷第
1
期
Vo
l.
46 NO.l
文章编号:
1671-9352
(2011
)
01
-0
∞
1
-0
5
山东大学
学
报(理学版)
Journal
of
Shandong
University
(Natural
Science)
2011
年
1
月
1an.
2011
手指自主按键运动中脑磁图信号的相干性分析
侯文生
l
,张
F
日
1
,李卫娜
2
,吴小鹰
l
,吴国材
2
,冯华
2
,郑小林
1
(1
.重
庆大学生物流变科学与技术教
育
部重点实验室,重庆
ωω44;
2
.
第二
军医大学附属西南
医院
神经外科,重庆
40
∞
38
)
摘要:为了获取手指运动过程中不同脑功能区之间的联系,以及这种功能性联系在时频域和空间的变化,记录了
与手指运动相关的脑磁图信号,然后对其进行相千性分析,并计算了不同位置信号之间的相千性系数。通过时频
分析进一步探讨了在
α(5
-15
Hz)
、
β
(l
6-25Hz)
、
lowγ(30
-45
Hz)3
个频带的不同皮层区联系随时间的变化关
系
。
结果表明
:α
、
9
、
lowγ3
个频带与所选参考信号相千性呈现出位置大致相同,相干强度和相干范围均从
α
到
lowγ
依次递减,相干性系数随时间而变化,进而推论出相干性的变化表明对侧运动皮层存在不同的神经模式,而
且这些神经模式也是随时间变化的,由此反映出不同功能区的联系在时频域的变化
。
关键词:脑磁图;运动;相干性;时频分析
中图分类号:R3
18
.
04
文献标志码
:A
Coherence analysis of magnetoencephalography
signals
related
to
self -paced finger
press
HOU
Wen-sheng
1
,
ZHANG
Yang
1
,
LI
Wei-na
2
,
WU
Xiao-ying
l
,
WU
Guo-cae
,
FENG
Hua
2
,
ZHENG
Xiao-lin
l
(1.
Key
Laboratory
of
Biorheological Science and Technology
,
Ministry
of
Education
,
Chongqing University
,
Chongqing 400044
,
China;
2.Dep
缸
tment
of Neurosurgery , Southwest
Hospital
,白山
d
Military Medical University , Chongqing 400038 , China)
Abstract:ηle
present study
was
aimed at
invωtigating
the connection between spatially separated brain regions
,
as
well
as the changes
of
the connection in time and frequency domain. Self-paced flllger press related magnetoencephalography
signals were recorded and analyzed
by
means
of
coherence analysis.
Th
e coherence coefficient
of
two signals corre-
sponding
to
different
cortical
缸
eas
was calculated.
Time
企
'equency
analysis
was
also used
to
deterrnine
if
the cortical
connection changes closely
co-v
缸
y
with time over the course
of
motor task
in
也
E
由
ree
frequency
band-α(5-15
Hz)
、
β
(16-25 Hz) and
lowγ(30
-4
5
Hz).
Th
e results showed that channels with the most significant coherence relative
to
由
e
selected reference channel were approximately in
the
s
创
ne
area
,
and with
an
increase
of
frequency band both the coher-
ence coefficient and the coupled area declined. Moreover
,
the coherence coefficient changed co-varied with time in the
three frequency band.
lt
was
infered that there are different neuronal modulations in the contralateral motor cortex
,
and
由
is
modulation co-varies with time
,
which consequently reflects
th
巳
changes
of
correlation between different brain
re-
gions in time and frequency domain.
Key words: magnetoencephalography; movement; coherence; time
frl
巳
quency
analysis
l
眩稿日期
:2010-10-16
基金项目:国家自然科
学基金资助项目
(
0770546;30970758)
;
重 庆市
自然
科学基金资助项目
(2006BB2043
;2007BB5148)
;重庆大学
"211
工程
"
三期创新人才培养计划建设项目
(5
-09
104
)
作者简介:侯文生
(
1968-
),男,博士,教授,博士生导师,主要研究
方
向为
生
物医学信息检测与处理、基于
MEM5
的微型医疗仪器设计
、
神
经工
程及康复
.
Email:
hw
s
21
cn
@yahoo
.
co
m.cn