"LBs中已知蛋白质功能统计及研究概述"

In the study of LBs (Lewy bodies), a type of abnormal protein aggregates found in the brains of patients with Parkinson's disease, a list of previously reported protein components in LBs was compiled. This list includes 14-3-3 protein epsilon (14-3-3 ε), which plays a role in cell signaling and apoptosis. The presence of this protein in LBs suggests a potential involvement of abnormal cell signaling pathways in the pathogenesis of Parkinson's disease. Other proteins identified in LBs include alpha-synuclein, ubiquitin, and parkin, all of which are known to be associated with neurodegenerative diseases. The diverse range of proteins found in LBs underscores the complexity of the disease process and highlights the need for further research to better understand the underlying mechanisms of Parkinson's disease.