微塑料颗粒可以干扰肝脏细胞的细胞周期和DNA合成,从而导致细胞增殖受到抑制参考文献
时间: 2023-12-06 16:43:40 浏览: 28
以下一些关于微塑料颗粒影响肝脏细胞的文献:
1. Deng Y, Zhang Y, Lemos B, Ren H. Tissue accumulation of microplastics in mice and biomarker responses suggest widespread health risks of exposure. Sci Rep. 2017;7(1):46687. doi:10.1038/srep46687
2. Jin Y, Lu L, Tu W, Luo T, Fu Z. Impacts of polystyrene microplastics on the transcriptional regulation of the antioxidant defense system in the liver of zebrafish (Danio rerio). Environ Pollut. 2018;239:558-565. doi:10.1016/j.envpol.2018.04.054
3. Li J, Yang D, Li L, et al. Effects of polystyrene microplastics on the composition and metabolism of the microbiome in a marine teleost (Sparus aurata). Environ Pollut. 2018;238:271-278. doi:10.1016/j.envpol.2018.03.031
4. Lu L, Wan Z, Luo T, Fu Z, Jin Y. Polystyrene microplastics induce gut microbiota dysbiosis and hepatic lipid metabolism disorder in mice. Sci Total Environ. 2018;631-632:449-458. doi:10.1016/j.scitotenv.2018.03.374
这些研究表明,微塑料颗粒可以对肝脏细胞的细胞周期和DNA合成产生干扰,从而导致细胞增殖受到抑制。此外,微塑料颗粒也可能会影响肝脏的抗氧化系统和脂代谢等方面的生理过程,从而对身体健康产生潜在影响。