检查一下：def CreateNewCustomeByRequestsPOST(cookies): url = "https://crm.baidu.com/polaris-web/sme-cust/addCust/add" data = { "custBaseInfo": { "custType": "0", "custName": "上海曜纵科技有限公司", "company": "", "custSource1": "1", "custSource2": "108", "provinceId": "31", "cityId": "39", "countryId": "459", "tradeType": "51", "firstTradeId": 2031, "secondTradeId": 203101, "remark": "", "regionValue": [ "31", "39", "459" ], "tradeValue": [ 2031, 203101 ] }, "contacts": [ { "contactBaseInfo": { "name": "wef", "gender": "1", "duty": "", "remark": "", "state": 1 }, "contactWays": [ { "contactType": 0, "contactInfo": "12365548975", "state": 0, "countryCode": 86 } ], "phoneList": [ { "contactType": 0, "contactInfo": "12365548975", "state": 0, "countryCode": 86 } ], "telList": [ { "contactType": 1, "contactInfo": "", "state": 0, "countryCode": 86, "areaCode": "", "extInfo": "" } ], "emailList": [ { "contactType": 6, "contactInfo": "", "state": 0 } ] } ], "websites": [], "addresses": [], "custpoolId": "" } res = requests.post(url, data=data, cookies=cookies) return res

根据你提供的代码，data 中的 "regionValue" 和 "tradeValue" 对应的值都是列表类型，但是在接口文档中并没有要求传入列表类型，可能是因为这个原因导致了错误。建议你修改为字符串类型，如下所示：

data = {
    "custBaseInfo": {
        "custType": "0",
        "custName": "上海曜纵科技有限公司",
        "company": "",
        "custSource1": "1",
        "custSource2": "108",
        "provinceId": "31",
        "cityId": "39",
        "countryId": "459",
        "tradeType": "51",
        "firstTradeId": "2031",  # 修改为字符串类型
        "secondTradeId": "203101",  # 修改为字符串类型
        "remark": "",
        "regionValue": "31,39,459",  # 修改为字符串类型
        "tradeValue": "2031,203101"  # 修改为字符串类型
    },
    "contacts": [
        {
            "contactBaseInfo": {
                "name": "wef",
                "gender": "1",
                "duty": "",
                "remark": "",
                "state": 1
            },
            "contactWays": [
                {
                    "contactType": 0,
                    "contactInfo": "12365548975",
                    "state": 0,
                    "countryCode": 86
                }
            ],
            "phoneList": [
                {
                    "contactType": 0,
                    "contactInfo": "12365548975",
                    "state": 0,
                    "countryCode": 86
                }
            ],
            "telList": [
                {
                    "contactType": 1,
                    "contactInfo": "",
                    "state": 0,
                    "countryCode": 86,
                    "areaCode": "",
                    "extInfo": ""
                }
            ],
            "emailList": [
                {
                    "contactType": 6,
                    "contactInfo": "",
                    "state": 0
                }
            ]
        }
    ],
    "websites": [],
    "addresses": [],
    "custpoolId": ""
}

修改后再试试看是否能够正常运行。