翻译以下文字为英文:对于直径不超过3cm 的肝脏寡转移灶,立体定向放射治疗(SBRT)可以取得较好的局部控制率。SBRT是一种精确的外放疗技术,采用单次高剂量(5-30 Gy)大分割(1-5次)照射,以取得类似外科手术的效果,又称之为立体定向消融放疗(SABR)。生物等效剂量(BED)与肿瘤控制率正相关,BED≥100 Gy有更高的局控率。SABR安全性较高,常见不良反应为肝功能异常290-292及胃肠道反应。Child-Pugh评分、胃肠道疾病史、全身治疗和肿瘤位置等需在实施SABR前评估。放射治疗计划设计时应避免危及胃肠、脊髓等器官的高剂量照射。
时间: 2023-02-25 14:55:39 浏览: 146
For liver oligometastases with a diameter not exceeding 3 cm, stereotactic radiotherapy (SBRT) can achieve better local control rates. SBRT is a precise external radiotherapy technique that uses a single high dose (5-30 Gy) of large fractionation (1-5 times) to achieve results similar to those of surgical resection, also known as stereotactic ablative radiotherapy (SABR). The biologically equivalent dose (BED) is positively correlated with tumor control rate, and a BED ≥100 Gy has a higher local control rate. SABR has a high safety profile, with common adverse reactions including liver function abnormality 290-292 and gastrointestinal reactions. Child-Pugh score, gastrointestinal disease history, systemic therapy and tumor location should be evaluated prior to SABR. When designing the radiotherapy plan, high-dose radiation should be avoided to organs such as the gastrointestinal tract and spine.
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